Interactor 1: DBHA (P0ACF0)
DNA-binding protein HU-alpha (HU-2) (NS2)
Gene: hupA

Interactor 2: DBHB (P0ACF4)
DNA-binding protein HU-beta (HU-1) (NS1)
Gene: hupB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 17360520, 19402753, 15690043, 12875839
Identification Methods x-ray crystallography, tandem affinity purification, circular dichroism, pull down, aut-page, molecular sieving, differential scanning calorimetry
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bac_DNA_binding~Bac_DNA_binding
Common GO terms GO:0003677 - DNA binding
GO:0005829 - cytosol
GO:0006270 - DNA replication initiation
GO:0006281 - DNA repair
GO:0006351 - DNA-templated transcription
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 90
Ec

1 90
+ Ec
+ Nv
+ Ec
+ Ec
+ Nv
+ Ec
+ Ec
+ Ec
+ Nv
+ Nv
+ Nv
+ Nv
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024