HitPredict

Interactor 1: DCUS (P0AEC8)
Sensor histidine kinase DcuS (EC 2.7.13.3) (Fumarate sensor)
Gene: DCUS

Interactor 2: DCUS (P0AEC8)
Sensor histidine kinase DcuS (EC 2.7.13.3) (Fumarate sensor)
Gene: DCUS

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 20453099, 22101843
Identification Methods comigration in sds page, cross-linking study, adenylate cyclase complementation, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c~HATPase_c, PAS~PAS, sCache_3_2~sCache_3_2, SPOB_a~SPOB_a
Common GO terms GO:0000155 - phosphorelay sensor kinase activity
GO:0000160 - phosphorelay signal transduction system
GO:0004673 - protein histidine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 543
Ec

1 543
+ Bs
+ Bs
+ At
+ At
+ At
+ Mx
+ Mx
+ Tm
+ Ss
+ Mx
+ Mx
+ Mx
+ Pa
+ Mx
+ Mx
+ Mx
+ Mx

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Last updated: 15 Jul 2024