Interactor 1: GYRB (P0AES6)
DNA gyrase subunit B (EC 5.6.2.2) (Type IIA topoisomerase subunit GyrB)
Gene: GYRB

Interactor 2: PARE (P20083)
DNA topoisomerase 4 subunit B (EC 5.6.2.2) (Topoisomerase IV subunit B)
Gene: PARE

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.759

The method score is based on:

Property Details
Experiments 19402753, 15690043
Identification Methods tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_gyraseB~DNA_gyraseB, DNA_gyraseB~DNA_gyraseB_C, DNA_gyraseB~HATPase_c, DNA_gyraseB~Toprim, DNA_gyraseB_C~DNA_gyraseB_C, DNA_gyraseB_C~Toprim, DNA_gyraseB_C~GyrB_insert, HATPase_c~HATPase_c, Toprim~Toprim
Common GO terms GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005694 - chromosome
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 804
Ec

1 630
+ Hs
+ Hs
+ Dm
+ Zm
+ Sc
+ Ec

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Last updated: 15 Jul 2024