Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA
Interactor 2: SRP54 (P61011)
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein)
Gene: SRP54
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33053321 |
| Identification Methods | molecular sieving, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SRP-alpha_N~SRP54, SRP-alpha_N~SRP54_N, SRP54~SRP54, SRP54~SRP54_N, SRP54~SRP_SPB, SRP54_N~SRP54_N, SRP54_N~SRP_SPB |
| Common GO terms | GO:0003723 - RNA binding GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition GO:0016887 - ATP hydrolysis activity and 1 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
