HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: MSH6 (P52701)
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
Gene: MSH6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	28242625, 35271311, 24463511
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 1360
+	Hs
		855539 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		MSH6_HUMAN (1-1360): 0: 1486: 100.00
+	Hs
		555365 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		MSH6_HUMAN (1-1360): 0: 1486: 100.00
+	Hs
		469962 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Hs
		391544 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		MSH3_HUMAN (173-1357): 0: 835: 22.16
+	Hs
		555334 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Hs
		331824 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		331703 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44
+	Hs
		331860 H2A1C_HUMAN (5-125): 5.99e-55: 169: 61.48		NSD2_HUMAN (4-411): 1.45e-80: 293: 17.44