HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 475
+	Hs
		391555 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		641916 H2AJ_HUMAN (1-126): 5.48e-65: 195: 96.03		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		470389 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		SART3_HUMAN (10-377): 4.33e-86: 285: 22.52
+	Hs
		391710 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		SART3_HUMAN (10-377): 4.33e-86: 285: 22.52
+	Hs
		1063214 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		SART3_HUMAN (10-377): 4.33e-86: 285: 22.52
+	Hs
		470365 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		555478 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		555437 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		594846 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		391695 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		1054520 H2A1A_HUMAN (1-130): 6.89e-67: 199: 93.13		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		470244 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		391681 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		516349 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35