HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	24981860, 34349018, 28514442, 33961781, 24463511
Identification Methods	affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 136
+	Hs
		934877 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086182 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		1086192 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		391649 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		470399 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		935170 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086293 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		391723 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		470350 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		1151344 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		1174619 H2A1C_HUMAN (1-130): 8.04e-68: 202: 98.46		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		391655 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		470427 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		1174640 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		391757 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		470413 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H37_HUMAN (1-136): 5.62e-59: 180: 97.06
+	Hs
		391740 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H37_HUMAN (1-136): 5.62e-59: 180: 97.06
+	Hs
		1157222 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		594830 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		391597 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00