HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34349018, 37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 136
+	Hs
		470336 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		934877 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086182 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		1086192 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		391649 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		935170 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086293 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		391723 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		470350 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1151344 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		1174619 H2A1C_HUMAN (1-130): 8.04e-68: 202: 98.46		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		391655 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		470427 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		1174640 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		391757 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		470413 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		H37_HUMAN (1-136): 1.11e-58: 179: 94.12
+	Hs
		391740 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		H37_HUMAN (1-136): 1.11e-58: 179: 94.12
+	Hs
		1157222 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		H3C_HUMAN (1-136): 2.16e-58: 178: 90.44
+	Hs
		594830 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Hs
		391597 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24