Interactor 1: IL6 (P08505)
Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)
Gene: IL6
Interactor 2: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21057510 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL6~fn3, IL6~IL6Ra-bind, IL6~Lep_receptor_Ig |
| Common GO terms | GO:0005138 - interleukin-6 receptor binding GO:0005896 - interleukin-6 receptor complex GO:0009897 - external side of plasma membrane GO:0070102 - interleukin-6-mediated signaling pathway |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
