HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	27462807
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 571
+	Hs
		1151353 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		1185204 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		391788 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		1087045 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		555539 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		555503 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		NIPBL_HUMAN (87-561): 1.57e-63: 228: 13.92
+	Hs
		1151358 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		391801 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		1087056 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		470480 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05
+	Hs
		391817 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05
+	Hs
		1264786 H2A1H_HUMAN (1-128): 4.17e-67: 200: 100.00		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05