HitPredict

Interactor 1: FBSP1 (P0C2W1)
F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)
Gene: FBXO45

Interactor 2: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 986
+	Hs
		1273256 SPSB4_HUMAN (88-280): 6.42e-75: 231: 41.41		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		1171093 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHG2_HUMAN (1-986): 0: 736: 100.00
+	Hs
		1016921 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		AKP13_HUMAN (37-964): 2.77e-144: 478: 35.95
+	Hs
		1016917 RN123_HUMAN (141-284): 2.46e-27: 113: 17.01		AKP13_HUMAN (37-964): 2.77e-144: 478: 35.95
+	Hs
		1170396 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHGI_HUMAN (1-982): 5.42e-125: 414: 30.77
+	Hs
		1172040 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHGC_HUMAN (64-975): 7.9e-104: 357: 16.93
+	Hs
		855804 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		VAV2_HUMAN (40-788): 3.5e-103: 344: 13.46
+	Hs
		1066031 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHG6_HUMAN (22-797): 1.34e-103: 343: 11.48
+	Hs
		1049713 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHG7_HUMAN (22-779): 1.98e-100: 335: 11.77
+	Hs
		1172216 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		VAV3_HUMAN (40-828): 1.15e-98: 331: 12.49
+	Hs
		167093 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHGB_HUMAN (109-915): 6.47e-88: 311: 21.18
+	Hs
		200777 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHG9_HUMAN (162-599): 2.49e-92: 305: 12.45
+	Hs
		1171081 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ARHG1_HUMAN (31-698): 5.2e-86: 298: 21.49
+	Hs
		1137757 RN123_HUMAN (141-284): 2.46e-27: 113: 17.01		OBSCN_HUMAN (181-949): 2.83e-85: 304: 13.20
+	Hs
		224719 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		KALRN_HUMAN (224-886): 6.14e-74: 270: 11.89
+	Hs
		1078848 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		ITSN1_HUMAN (222-600): 5.07e-70: 257: 22.28
+	Hs
		279875 TRI67_HUMAN (105-277): 7.29e-38: 143: 21.02		TRIO_HUMAN (224-927): 2.52e-66: 246: 12.28
+	Hs
		1078838 RN123_HUMAN (141-284): 2.46e-27: 113: 17.01		ITSN1_HUMAN (222-600): 5.07e-70: 257: 22.28