HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 197
+	Hs
		473934 NFIC_HUMAN (1-508): 1.62e-162: 472: 100.00		TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59
+	Hs
		473932 NFIC_HUMAN (1-508): 1.62e-162: 472: 100.00		TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50
+	Hs
		1047818 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50
+	Hs
		473933 NFIC_HUMAN (1-508): 1.62e-162: 472: 100.00		TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50
+	Hs
		1047975 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50
+	Hs
		1061698 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		TLE5_HUMAN (1-197): 3.11e-101: 292: 100.00
+	Hs
		1048153 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59
+	Hs
		1047806 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50
+	Hs
		142955 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		TLE4_HUMAN (2-191): 3.59e-112: 338: 68.59
+	Hs
		1047960 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50
+	Hs
		142953 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50
+	Hs
		142954 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50
+	Hs
		1061677 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		TLE5_HUMAN (1-197): 3.11e-101: 292: 100.00
+	Hs
		142966 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		TLE5_HUMAN (1-197): 3.11e-101: 292: 100.00
+	Hs
		1047877 RERE_HUMAN (185-495): 5.5e-30: 126: 13.87		TLE1_HUMAN (2-197): 2.48e-111: 336: 64.50
+	Hs
		1048118 RERE_HUMAN (185-495): 5.5e-30: 126: 13.87		TLE3_HUMAN (2-197): 3.96e-105: 320: 61.50