Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC
Interactor 2: UBA1 (P22314)
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)
Gene: UBA1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.963 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30279270, 27182664, 23003343, 24816100, 28190767, 17980597, 34642328, 17550899 |
| Identification Methods | x-ray crystallography, enzymatic study, unspecified method, biochemical, pull down, proximity labelling technology, affinity chromatography technology |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ThiF~ubiquitin |
| Common GO terms | GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination and 1 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
