Protein: IF4F2
Eukaryotic initiation factor 4F subunit p130 (eIF-4F p130) (eIF4F p130) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 2) (eIF4G2) (mRNA cap-binding protein complex subunit p130)

Gene: IF4F2, TIF4632
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P39936

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0001671 - ATPase activator activity
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005840 - ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

453954

IF4E
Eukaryotic translation initiation factor 4E

8

18

Small-scale

0.971

High

518299

IF4A
ATP-dependent RNA helicase eIF4A

6

20

Small-scale

0.951

High

757492

NCBP1
Nuclear cap-binding protein complex subunit 1

4

6

High-throughput

0.892

High

444524

DED1
ATP-dependent RNA helicase DED1

4

12

Small-scale

0.890

High

815122

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

10

High-throughput

0.776

High

403521

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

11

17

Small-scale

0.762

High

740928

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

4

20

High-throughput

0.691

High

815340

NCBP2
Nuclear cap-binding protein subunit 2

6

14

Small-scale

0.668

High

815326

NAM8
Protein NAM8

3

15

High-throughput

0.662

High

815343

YRA1
RNA annealing protein YRA1

3

19

Small-scale

0.640

High

751404

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

2

High-throughput

0.628

High

748176

SUI1
Eukaryotic translation initiation factor eIF-1

2

2

Small-scale

0.624

High

795764

HEK2
Heterogeneous nuclear rnp K-like protein 2

2

17

High-throughput

0.621

High

518028

SSBP1
Single-stranded nucleic acid-binding protein

2

20

Small-scale

0.619

High

815304

SGN1
RNA-binding protein SGN1

3

15

High-throughput

0.613

High

738850

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

High-throughput

0.601

High

813980

IF2P
Eukaryotic translation initiation factor 5B

2

1

Small-scale

0.584

High

815314

PSP2
Protein PSP2

2

0

Small-scale

0.576

High

799748

IF5
Eukaryotic translation initiation factor 5

1

5

Small-scale

0.561

High

815332

DHR1
Probable ATP-dependent RNA helicase DHR1

1

11

High-throughput

0.553

High

815337

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

15

Small-scale

0.553

High

815338

PRP11
Pre-mRNA-splicing factor PRP11

2

2

Small-scale

0.552

High

700242

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

1

High-throughput

0.537

High

776469

MPE1
Protein MPE1

2

1

High-throughput

0.537

High

632898

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

3

High-throughput

0.536

High

815321

NRD1
Protein NRD1

1

1

High-throughput

0.536

High

815323

CBK1
Serine/threonine-protein kinase CBK1

1

9

High-throughput

0.536

High

410151

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.533

High

433657

RL26A
Large ribosomal subunit protein uL24A

2

2

High-throughput

0.533

High

674641

RS2
Small ribosomal subunit protein uS5

2

3

Small-scale

0.533

High

815306

DSN1
Kinetochore-associated protein DSN1

2

2

High-throughput

0.533

High

804181

SSZ1
Ribosome-associated complex subunit SSZ1

2

10

High-throughput

0.504

High

364550

CDK1
Cyclin-dependent kinase 1

1

5

Small-scale

0.501

High

801833

KSP1
Serine/threonine-protein kinase KSP1

1

8

Small-scale

0.501

High

815308

SCD6
Protein SCD6

1

1

Small-scale

0.501

High

815327

NOP3
Serine/arginine

1

20

Small-scale

0.501

High

382112

H4
Histone H4

1

8

High-throughput

0.489

High

644662

MAG
DNA-3-methyladenine glycosylase

1

1

High-throughput

0.489

High

721958

XPO1
Exportin-1

1

12

High-throughput

0.489

High

737090

CDC11
Cell division control protein 11

1

8

High-throughput

0.489

High

800608

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

8

High-throughput

0.489

High

815335

MAG2
E3 ubiquitin-protein ligase MAG2

1

1

High-throughput

0.489

High

815320

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.486

High

438701

SC160
Protein SCP160

1

15

High-throughput

0.479

High

441922

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

645427

XRN1
5'-3' exoribonuclease 1

1

3

Small-scale

0.479

High

689042

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

747379

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

757656

IF4B
Eukaryotic translation initiation factor 4B

1

2

Small-scale

0.479

High

780828

MUD2
Splicing factor MUD2

1

1

Small-scale

0.479

High

796578

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

Small-scale

0.479

High

802190

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

815300

LSM4
LSM complex subunit LSM4

1

1

Small-scale

0.479

High

815310

LSM1
LSM1-LSM7 complex subunit LSM1

1

4

Small-scale

0.479

High

815319

EIF2A
Eukaryotic translation initiation factor 2A

1

10

High-throughput

0.479

High

815322

GIS2
Zinc finger protein GIS2

1

3

Small-scale

0.479

High

815342

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

815344

BBP
Branchpoint-bridging protein

1

7

Small-scale

0.479

High

585282

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.470

High

815317

SNU71
U1 small nuclear ribonucleoprotein component SNU71

1

1

Small-scale

0.457

High

438438

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

10

Small-scale

0.445

High

678682

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

6

High-throughput

0.445

High

815345

GDIR
Rho GDP-dissociation inhibitor

1

1

High-throughput

0.439

High

149779

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

381105

H2B1
Histone H2B.1

1

8

High-throughput

0.437

High

383715

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

427291

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.437

High

432593

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.437

High

432850

RL9A
Large ribosomal subunit protein uL6A

1

2

High-throughput

0.437

High

433214

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.437

High

434027

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.437

High

434381

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.437

High

434578

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

435112

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

435983

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

436422

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.437

High

455077

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

503059

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504227

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

512454

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

513023

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

514651

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

528826

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.437

High

531752

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.437

High

570026

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.437

High

579437

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.437

High

594379

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.437

High

601053

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.437

High

684739

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.437

High

689472

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

712578

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.437

High

743525

RU1A
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.437

High

745749

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.437

High

747868

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

753387

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

778344

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

780451

SRPB
Signal recognition particle receptor subunit beta

1

3

High-throughput

0.437

High

792062

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.437

High

792814

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.437

High

797742

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.437

High

812318

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

815301

TM108
Protein TMA108

1

1

High-throughput

0.437

High

815302

RL34B
Large ribosomal subunit protein eL34B

1

2

High-throughput

0.437

High

815303

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.437

High

815307

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.437

High

815309

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.437

High

815311

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

815312

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

815315

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.437

High

815316

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.437

High

815318

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.437

High

815325

RL34A
Large ribosomal subunit protein eL34A

1

2

High-throughput

0.437

High

815328

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.437

High

815329

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.437

High

815330

HMO1
High mobility group protein 1

1

15

High-throughput

0.437

High

815331

SIZ1
E3 SUMO-protein ligase SIZ1

1

6

High-throughput

0.437

High

815334

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.437

High

815336

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

815339

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

815341

AP3D
AP-3 complex subunit delta

1

10

High-throughput

0.437

High

815346

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.437

High

460976

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.407

High

526760

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.407

High

544963

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.407

High

645930

DBF2
Cell cycle protein kinase DBF2

1

12

High-throughput

0.407

High

752291

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.407

High

815305

DJP1
DnaJ-like protein 1

1

2

High-throughput

0.407

High

815324

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

2

High-throughput

0.407

High

815333

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.282

High

665182

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.269

Low

383133

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.249

Low

433027

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.249

Low

513690

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

515369

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.249

Low

792525

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.249

Low

815313

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.249

Low

427032

FUR4
Uracil permease

1

0

High-throughput

0.232

Low

454448

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.232

Low

602124

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.232

Low

815299

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025