HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 525
+	Hs
		475390 UBC_HUMAN (1-685): 0: 846: 100.00		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		408535 UBC_HUMAN (1-685): 0: 846: 100.00		KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92
+	Hs
		475314 UBC_HUMAN (1-685): 0: 846: 100.00		KPCA_HUMAN (4-419): 2.83e-142: 426: 35.55
+	Hs
		116959 UBC_HUMAN (1-685): 0: 846: 100.00		SGK1_HUMAN (79-417): 5.26e-101: 312: 46.44
+	Hs
		681773 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		923962 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		KPCE_HUMAN (13-420): 6.39e-143: 430: 33.89
+	Rn
		934619 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCB_RAT (35-422): 4.52e-146: 436: 36.92
+	Hs
		474936 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT2_HUMAN (3-416): 5.02e-151: 442: 38.66
+	Hs
		474935 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		408534 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92