HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: JOS1 (Q15040)
Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1)
Gene: JOSD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.899

Property	Details
Experiments	29576527, 21118805, 19382171, 23625928
Identification Methods	pull down, enzymatic study, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Josephin~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 202
+	Hs
		476081 UBC_HUMAN (1-685): 0: 846: 100.00		JOS2_HUMAN (20-201): 6.2e-81: 240: 55.19
+	Hs
		475519 UBC_HUMAN (1-685): 0: 846: 100.00		ATX3_HUMAN (25-187): 8.96e-57: 184: 24.44
+	Hs
		476365 UBC_HUMAN (1-685): 0: 846: 100.00		ATX3L_HUMAN (26-187): 2.12e-55: 181: 26.26
+	Mm
		476980 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ATX3_MOUSE (25-187): 1.35e-56: 184: 24.44
+	Hs
		474967 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ATX3_HUMAN (25-187): 8.96e-57: 184: 24.44