HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22045334
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 467
+	Hs
		475623 UBC_HUMAN (1-685): 0: 846: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		475815 UBC_HUMAN (1-685): 0: 846: 100.00		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Hs
		475717 UBC_HUMAN (1-685): 0: 846: 100.00		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58
+	Hs
		1078562 Q5RKT7_HUMAN (609-684): 5.63e-41: 148: 100.00		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		924009 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Rn
		250836 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SMAD2_RAT (1-467): 0: 674: 99.36
+	Hs
		397950 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58