Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: OTU1 (Q5VVQ6)
Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (DUBA-8) (HIV-1-induced protease 7) (HIN-7) (HsHIN7) (OTU domain-containing protein 2)
Gene: YOD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 27753622, 32296183, 38803224, 19818707, 27066941, 23827681, unassigned1304
Identification Methods pull down, two hybrid, enzymatic study, x-ray crystallography, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains OTU~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 685
Hs

1 348
+ Hs
+ Rn
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024