HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 130
+	Hs
		391519 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		476271 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66
+	Hs
		476233 UBC_HUMAN (1-685): 0: 846: 100.00		H2A1A_HUMAN (1-125): 8.62e-66: 197: 95.20
+	Hs
		475833 UBC_HUMAN (1-685): 0: 846: 100.00		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		475312 UBC_HUMAN (1-685): 0: 846: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392250 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	At
		1092092 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		H2A6_ARATH (1-128): 3.69e-59: 180: 71.32
+	Dm
		950447 R9PY16_DROME (457-685): 5.07e-80: 258: 90.39		H2A_DROME (17-125): 2.5e-59: 180: 89.91
+	Hs
		924034 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Hs
		391643 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470331 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		924049 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69
+	Hs
		555403 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Rn
		474085 UBC_RAT (1-108): 1.27e-29: 127: 90.74		H2A2A_RAT (1-130): 4.66e-67: 200: 100.00
+	Hs
		474911 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		470393 OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46