Protein: AL3B1
Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.28) (EC 1.2.1.5) (EC 1.2.1.7) (Aldehyde dehydrogenase 7) (Long-chain fatty aldehyde dehydrogenase) (EC 1.2.1.48) (Medium-chain fatty aldehyde dehydrogenase)

Gene: AL3B1, ALDH3B1
Organism: Homo sapiens
Interactions: 127
UniProt ID: P43353

Gene Ontology (top 5):
GO:0004028 - 3-chloroallyl aldehyde dehydrogenase activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848007

AL3B2
Aldehyde dehydrogenase family 3 member B2

3

14

High-throughput

0.855

High

271964

OBSL1
Obscurin-like protein 1

4

3

High-throughput

0.691

High

848014

KR108
Keratin-associated protein 10-8

3

8

High-throughput

0.675

High

291244

NU155
Nuclear pore complex protein Nup155

3

4

High-throughput

0.662

High

848052

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

3

2

High-throughput

0.662

High

848036

WDR73
Integrator complex assembly factor WDR73

3

0

High-throughput

0.638

High

776935

PPM1A
Protein phosphatase 1A

3

0

High-throughput

0.634

High

60493

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

2

1

High-throughput

0.628

High

848006

IREB2
Iron-responsive element-binding protein 2

2

5

High-throughput

0.628

High

848020

DMWD
Dystrophia myotonica WD repeat-containing protein

2

4

High-throughput

0.628

High

848049

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

2

2

High-throughput

0.628

High

848053

SL9A6
Sodium/hydrogen exchanger 6

2

2

High-throughput

0.628

High

347565

BAG3
BAG family molecular chaperone regulator 3

2

1

High-throughput

0.611

High

570372

GFAP
Glial fibrillary acidic protein

2

3

High-throughput

0.611

High

300315

KRT34
Keratin, type I cuticular Ha4

2

2

High-throughput

0.606

High

685815

KRA59
Keratin-associated protein 5-9

2

10

High-throughput

0.606

High

848019

KRA11
Keratin-associated protein 1-1

2

8

High-throughput

0.606

High

848045

KRA13
Keratin-associated protein 1-3

2

8

High-throughput

0.606

High

848089

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

7

High-throughput

0.606

High

48345

UBA6
Ubiquitin-like modifier-activating enzyme 6

2

0

High-throughput

0.602

High

848085

FMN2
Formin-2

2

0

High-throughput

0.602

High

258796

DNJA2
DnaJ homolog subfamily A member 2

2

4

High-throughput

0.601

High

70137

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

848010

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.580

High

848071

KRA33
Keratin-associated protein 3-3

2

0

High-throughput

0.580

High

848021

CHIT1
Chitotriosidase-1

2

1

High-throughput

0.574

High

848013

KR107
Keratin-associated protein 10-7

1

8

High-throughput

0.573

High

848015

KR109
Keratin-associated protein 10-9

1

9

High-throughput

0.573

High

848024

K1H1
Keratin, type I cuticular Ha1

1

2

High-throughput

0.573

High

848034

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.573

High

848042

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.573

High

848070

KRA42
Keratin-associated protein 4-2

1

8

High-throughput

0.560

High

127647

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

4

High-throughput

0.536

High

136327

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

2

High-throughput

0.536

High

182491

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

260844

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.536

High

331721

MTMR5
Myotubularin-related protein 5

1

2

High-throughput

0.536

High

334155

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

High-throughput

0.536

High

418615

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

1

High-throughput

0.536

High

536686

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.536

High

674960

TNR6
Tumor necrosis factor receptor superfamily member 6

1

4

High-throughput

0.536

High

848009

HSP72
Heat shock-related 70 kDa protein 2

1

6

High-throughput

0.536

High

848018

TBA4A
Tubulin alpha-4A chain

1

5

High-throughput

0.536

High

848026

PRSS8
Prostasin

1

2

High-throughput

0.536

High

848031

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.536

High

848041

TBA1A
Tubulin alpha-1A chain

1

5

High-throughput

0.536

High

848044

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

1

High-throughput

0.536

High

848047

WDTC1
WD and tetratricopeptide repeats protein 1

1

9

High-throughput

0.536

High

848051

MADD
MAP kinase-activating death domain protein

1

1

High-throughput

0.536

High

848055

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

848060

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.536

High

848066

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.536

High

848069

TCAB1
Telomerase Cajal body protein 1

1

5

High-throughput

0.536

High

848073

CHIA
Acidic mammalian chitinase

1

1

High-throughput

0.536

High

848078

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

2

High-throughput

0.536

High

848081

WDR6
tRNA

1

6

High-throughput

0.536

High

848086

E2AK4
eIF-2-alpha kinase GCN2

1

2

High-throughput

0.536

High

848091

CHIP
E3 ubiquitin-protein ligase CHIP

1

7

High-throughput

0.536

High

848093

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.536

High

848012

KR105
Keratin-associated protein 10-5

1

9

High-throughput

0.515

High

575643

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.513

High

600600

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.513

High

610562

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.513

High

844988

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

848008

HXK2
Hexokinase-2

1

0

High-throughput

0.513

High

848022

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.513

High

848038

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

0

High-throughput

0.513

High

848040

SE6L2
Seizure 6-like protein 2

1

0

High-throughput

0.513

High

848064

METH
Methionine synthase

1

0

High-throughput

0.513

High

848068

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.513

High

848074

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.513

High

848084

SPHK1
Sphingosine kinase 1

1

0

High-throughput

0.513

High

848087

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.513

High

848027

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

848032

ZMYM4
Zinc finger MYM-type protein 4

1

1

High-throughput

0.489

High

848037

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.489

High

848046

CDK20
Cyclin-dependent kinase 20

1

1

High-throughput

0.489

High

848062

INT14
Integrator complex subunit 14

1

1

High-throughput

0.489

High

848011

KR103
Keratin-associated protein 10-3

1

9

High-throughput

0.481

High

848065

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

Small-scale

0.481

High

362935

EGFR
Epidermal growth factor receptor

1

9

Small-scale

0.479

High

761342

HS71L
Heat shock 70 kDa protein 1-like

1

6

High-throughput

0.479

High

766142

NOS2
Nitric oxide synthase, inducible

1

1

High-throughput

0.479

High

848033

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

848039

TRI65
E3 ubiquitin-protein ligase TRIM65

1

1

High-throughput

0.479

High

848048

LIRA3
Leukocyte immunoglobulin-like receptor subfamily A member 3

1

2

High-throughput

0.479

High

848077

TBB1
Tubulin beta-1 chain

1

2

High-throughput

0.479

High

848083

FXL12
F-box/LRR-repeat protein 12

1

3

Small-scale

0.479

High

848090

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

848023

SNX17
Sorting nexin-17

1

0

High-throughput

0.458

High

848063

T22D3
TSC22 domain family protein 3

1

0

High-throughput

0.458

High

848067

APOL2
Apolipoprotein L2

1

0

High-throughput

0.458

High

226721

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

8

High-throughput

0.445

High

475912

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

1

High-throughput

0.445

High

516186

HS71B
Heat shock 70 kDa protein 1B

1

6

High-throughput

0.445

High

633417

ANPRB
Atrial natriuretic peptide receptor 2

1

1

High-throughput

0.445

High

848017

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

6

High-throughput

0.445

High

848029

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.445

High

848061

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

High-throughput

0.445

High

848092

RAP2C
Ras-related protein Rap-2c

1

3

High-throughput

0.445

High

161289

ENC1
Ectoderm-neural cortex protein 1

1

0

High-throughput

0.426

High

239020

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.426

High

334611

LYPA2
Acyl-protein thioesterase 2

1

0

High-throughput

0.426

High

391198

FRIL
Ferritin light chain

1

0

High-throughput

0.426

High

848005

MAOX
NADP-dependent malic enzyme

1

0

High-throughput

0.426

High

848059

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.426

High

848072

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.426

High

848080

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.426

High

848058

SAAL1
Protein SAAL1

1

1

High-throughput

0.407

High

848079

LRC40
Leucine-rich repeat-containing protein 40

1

1

High-throughput

0.407

High

848054

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

3

0

High-throughput

0.347

High

848016

SELT
Thioredoxin reductase-like selenoprotein T

2

0

High-throughput

0.328

High

848030

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

2

0

High-throughput

0.313

High

261477

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

271195

ASTN2
Astrotactin-2

1

0

High-throughput

0.279

Low

848035

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.279

Low

848043

TLK2
Serine/threonine-protein kinase tousled-like 2

1

0

High-throughput

0.279

Low

848050

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

848057

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

848075

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

848088

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

848025

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.249

Low

848076

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.249

Low

296691

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.232

Low

848028

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low

848056

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.232

Low

848082

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025