HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TM1L2 (Q6ZVM7)
TOM1-like protein 2 (Target of Myb-like protein 2)
Gene: TOM1L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	28190767, 31699778, 37019113, 38803224, 23314748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	GAT~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 507
+	Hs
		241137 UBC_HUMAN (1-685): 0: 846: 100.00		TOM1_HUMAN (1-507): 1.07e-155: 454: 61.40
+	Hs
		272789 UBC_HUMAN (1-685): 0: 846: 100.00		TM1L1_HUMAN (7-468): 4.22e-95: 298: 29.90
+	Hs
		476541 UBC_HUMAN (1-685): 0: 846: 100.00		GGA1_HUMAN (13-474): 5.55e-93: 297: 22.74
+	Hs
		476138 UBC_HUMAN (1-685): 0: 846: 100.00		STAM1_HUMAN (1-491): 2.46e-92: 293: 19.80
+	Hs
		476481 UBC_HUMAN (1-685): 0: 846: 100.00		GGA3_HUMAN (12-497): 1.56e-90: 293: 20.36
+	Hs
		276993 UBC_HUMAN (1-685): 0: 846: 100.00		STAM2_HUMAN (1-501): 1.54e-83: 269: 17.97
+	Bt
		477668 UBC_BOVIN (1-613): 0: 753: 99.18		Q58CQ6_BOVIN (13-407): 5.41e-91: 286: 23.27
+	Hs
		159860 UBC_HUMAN (1-685): 0: 846: 100.00		HGS_HUMAN (13-166): 1.32e-41: 160: 33.55
+	Dm
		477530 UBIQP_DROME (1-610): 0: 752: 99.84		HRS_DROME (9-167): 1.95e-40: 157: 34.36
+	Sc
		477454 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA1_YEAST (10-429): 2.68e-71: 238: 18.65
+	Sc
		477270 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA2_YEAST (11-378): 1.03e-68: 232: 21.80
+	Mm
		292209 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TOM1_MOUSE (1-507): 1.21e-159: 464: 60.86
+	Ce
		477552 UBIQ1_CAEEL (1-229): 5.97e-87: 292: 98.25		Q17796_CAEEL (10-400): 2.19e-69: 237: 16.98
+	At
		285943 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		TOL6_ARATH (18-392): 1.72e-69: 236: 25.82
+	At
		1092009 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		TOL5_ARATH (13-423): 4.41e-69: 229: 19.77
+	Ce
		136432 UBIQ1_CAEEL (1-229): 5.97e-87: 292: 98.25		STAM1_CAEEL (9-432): 1.65e-60: 207: 15.86
+	Hs
		924099 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM1_HUMAN (1-491): 2.46e-92: 293: 19.80
+	Mm
		476756 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM1_MOUSE (1-491): 4.75e-95: 300: 20.40
+	Hs
		277047 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM2_HUMAN (1-501): 1.54e-83: 269: 17.97
+	Mm
		292343 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM2_MOUSE (1-496): 7.06e-89: 283: 18.65