HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.980

Property	Details
Experiments	26451915, 29398621, 29940186, 32296183, 28190767, 30659753, 38803224, 19285159, unassigned1304, 18239685
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology, two hybrid, unspecified method, protein array, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	Zn-C2H2_12~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 789
+	Hs
		475695 UBC_HUMAN (1-685): 0: 846: 100.00		CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00
+	Hs
		475291 UBC_HUMAN (1-685): 0: 846: 100.00		MYH1_HUMAN (181-778): 1.83e-23: 109: 9.33
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (412-783): 9.06e-12: 71.2: 9.68
+	Hs
		1025496 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00
+	Hs
		924056 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TAXB1_HUMAN (1-789): 5.15e-85: 288: 100.00
+	Hs
		475085 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		TAXB1_HUMAN (1-789): 5.15e-85: 288: 100.00
+	Mm
		476794 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TAXB1_MOUSE (1-789): 9.67e-73: 255: 82.23
+	Hs
		923972 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00
+	Hs
		1025420 Q5U5U6_HUMAN (1-77): 7.83e-26: 108: 98.70		CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00
+	Hs
		475014 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CACO2_HUMAN (7-339): 2.16e-36: 144: 27.00
+	Hs
		148651 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CTRO_HUMAN (96-665): 2.04e-20: 99.2: 11.44
+	Rn
		655929 UBC_RAT (1-108): 1.27e-29: 127: 90.74		DCTN1_RAT (173-498): 1.15e-16: 86.9: 19.47
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (290-747): 2.19e-15: 83.2: 10.04
+	Mm
		476960 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYO5A_MOUSE (269-660): 6.97e-14: 78: 14.63
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (423-783): 8.76e-12: 71.2: 9.37
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (290-756): 5.81e-16: 84.7: 10.02
+	Hs
		398149 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYO5A_HUMAN (269-660): 1.32e-13: 77.3: 14.15
+	Hs
		398052 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MY18A_HUMAN (251-658): 5.76e-13: 75: 11.46
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (412-783): 9.06e-12: 71.2: 9.68
+	Hs
		398086 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		UACA_HUMAN (145-584): 3.36e-09: 62.6: 17.62