Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: NPL4 (Q8TAT6)
Nuclear protein localization protein 4 homolog (Protein NPL4)
Gene: NPLOC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 28525741, 12644454, 25752573, 28190767, 35271311, 34642328, 38803224, 16196087, 17550899, 17070805
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NPL4~ubiquitin, ubiquitin~zf-NPL4
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 685
Hs

1 608
+ Mm
+ Hs
+ Sc

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Last updated: 15 Jul 2024