HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TRI36 (Q9NQ86)
E3 ubiquitin-protein ligase TRIM36 (EC 2.3.2.27) (RING finger protein 98) (RING-type E3 ubiquitin transferase TRIM36) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
Gene: TRIM36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19232519
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 728
+	Hs
		175634 UBC_HUMAN (1-685): 0: 846: 100.00		TRI18_HUMAN (24-728): 5.52e-124: 386: 23.45
+	Hs
		475753 UBC_HUMAN (1-685): 0: 846: 100.00		TRI25_HUMAN (22-723): 2.29e-89: 294: 15.09
+	Hs
		475423 UBC_HUMAN (1-685): 0: 846: 100.00		TRI23_HUMAN (18-401): 1.28e-56: 204: 21.60
+	Hs
		476418 UBC_HUMAN (1-685): 0: 846: 100.00		TRI39_HUMAN (129-519): 4.1e-47: 176: 12.77
+	Hs
		475704 UBC_HUMAN (1-685): 0: 846: 100.00		TIF1B_HUMAN (25-394): 1.78e-43: 170: 16.36
+	Hs
		476021 UBC_HUMAN (1-685): 0: 846: 100.00		TRI59_HUMAN (24-376): 1.65e-43: 163: 18.77
+	Hs
		475680 UBC_HUMAN (1-685): 0: 846: 100.00		TRI26_HUMAN (20-436): 2.96e-30: 127: 9.98
+	Hs
		475297 UBC_HUMAN (1-685): 0: 846: 100.00		TRI27_HUMAN (22-388): 9.56e-17: 85.9: 12.34
+	Hs
		475328 UBC_HUMAN (1-685): 0: 846: 100.00		RO52_HUMAN (29-134): 4.52e-10: 64.8: 14.29
+	Xl
		1186351 Q7SY79_XENLA (77-685): 0: 744: 99.84		NF7B_XENLA (3-528): 7.35e-21: 99.4: 11.84
+	Hs
		924042 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRI67_HUMAN (59-721): 1.89e-95: 315: 20.91
+	Hs
		923989 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRI25_HUMAN (22-723): 2.29e-89: 294: 15.09
+	Mm
		476671 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		RO52_MOUSE (134-514): 2.54e-39: 153: 11.46
+	Hs
		170323 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TIF1A_HUMAN (32-511): 1.62e-63: 231: 15.48
+	Rn
		88684 UBC_RAT (1-108): 1.27e-29: 127: 90.74		TRIM2_RAT (119-692): 4.52e-65: 231: 12.16
+	Hs
		734585 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRI23_HUMAN (18-401): 1.28e-56: 204: 21.60
+	Rn
		734823 UBC_RAT (1-108): 1.27e-29: 127: 90.74		TRI23_RAT (18-401): 5.07e-60: 214: 21.41
+	Hs
		923976 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TIF1B_HUMAN (25-394): 1.78e-43: 170: 16.36
+	Mm
		924236 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		RO52_MOUSE (134-514): 2.54e-39: 153: 11.46
+	Mm
		476831 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RO52_MOUSE (134-514): 2.54e-39: 153: 11.46