HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	26971995, 29398621, 31371777, 28190767, 38803224, 16196087, 17550899
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1294
+	Hs
		924214 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Mm
		477072 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		V9GX76_MOUSE (1-1294): 0: 1075: 95.98
+	Hs
		398137 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		475240 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		475417 UBC_HUMAN (1-685): 0: 846: 100.00		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	At
		98845 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		MYO17_ARATH (1060-1245): 2.49e-09: 64.2: 7.53
+	Hs
		398102 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Mm
		476960 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYO5A_MOUSE (710-1184): 1.64e-18: 94.2: 8.65
+	Mm
		476930 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH9_MOUSE (765-1178): 3.23e-12: 73.5: 14.05
+	Mm
		476828 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		MYH10_MOUSE (762-1135): 6.81e-09: 62.8: 16.00
+	Hs
		64575 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH7B_HUMAN (761-1095): 2.05e-11: 71.2: 14.33
+	Hs
		397813 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		397814 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		398149 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72