HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: POLI (Q9UNA4)
DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)
Gene: POLI

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.710

Property	Details
Experiments	23248005, 30659753, 31699778, 16763556, 20159559
Identification Methods	far western blotting, unspecified method, pull down, two hybrid, x-ray crystallography
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 740
+	Hs
		476588 UBC_HUMAN (1-685): 0: 846: 100.00		POLH_HUMAN (49-708): 1.34e-170: 508: 21.72
+	Hs
		476512 UBC_HUMAN (1-685): 0: 846: 100.00		REV1_HUMAN (27-727): 1.75e-163: 506: 18.45
+	Hs
		475244 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		POLI_HUMAN (1-740): 0: 772: 100.00
+	Mm
		476850 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		POLI_MOUSE (26-740): 0: 745: 76.94
+	Sc
		477433 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		POLH_YEAST (31-530): 5e-112: 354: 17.90
+	Mm
		476678 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		POLK_MOUSE (35-692): 1.22e-142: 441: 19.67
+	Sc
		477092 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		REV1_YEAST (54-558): 6.3e-101: 334: 17.04
+	Mm
		476951 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		REV1_MOUSE (27-716): 2.72e-163: 506: 19.49
+	Mm
		477038 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		POLK_MOUSE (35-692): 1.22e-142: 441: 19.67