Protein: SF3B1
U2 snRNP component HSH155

Gene: SF3B1, HSH155
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P49955

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892776

CUS1
Cold sensitive U2 snRNA suppressor 1

9

2

Small-scale

0.971

High

892768

CUS2
Cold sensitive U2 snRNA suppressor 2

5

15

Small-scale

0.922

High

892791

RDS3
Pre-mRNA-splicing factor RDS3

4

1

Small-scale

0.886

High

892795

NCBP2
Nuclear cap-binding protein subunit 2

2

10

High-throughput

0.754

High

892804

HSH49
Protein HSH49

2

9

Small-scale

0.754

High

892797

CWC2
Pre-mRNA-splicing factor CWC2

2

6

High-throughput

0.737

High

892786

RSE1
Pre-mRNA-splicing factor RSE1

6

6

Small-scale

0.734

High

892796

RU2A
U2 small nuclear ribonucleoprotein A'

6

6

Small-scale

0.729

High

638012

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

5

8

Small-scale

0.715

High

892781

CEF1
Pre-mRNA-splicing factor CEF1

4

7

High-throughput

0.699

High

826522

IST3
U2 snRNP component IST3

1

10

Small-scale

0.691

High

739164

PRP19
Pre-mRNA-processing factor 19

4

20

Small-scale

0.691

High

817126

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

3

High-throughput

0.686

High

892800

CLF1
Pre-mRNA-splicing factor CLF1

4

12

Small-scale

0.682

High

700120

PRP45
Pre-mRNA-processing protein 45

3

6

High-throughput

0.662

High

744130

BRR2
Pre-mRNA-splicing helicase BRR2

3

12

Small-scale

0.656

High

501742

YSF3
RDS3 complex subunit 10

4

0

Small-scale

0.653

High

892792

PRP11
Pre-mRNA-splicing factor PRP11

3

1

High-throughput

0.650

High

820820

RUXG
Small nuclear ribonucleoprotein G

3

6

High-throughput

0.643

High

892770

RUXF
Small nuclear ribonucleoprotein F

3

2

High-throughput

0.643

High

863086

CWC26
Pre-mRNA-splicing factor CWC26

3

1

Small-scale

0.637

High

892793

LUC7
Protein LUC7

2

2

High-throughput

0.621

High

740994

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

9

High-throughput

0.618

High

892773

NAM8
Protein NAM8

1

6

High-throughput

0.618

High

739255

PRP21
Pre-mRNA-splicing factor PRP21

2

2

High-throughput

0.611

High

892767

CWC22
Pre-mRNA-splicing factor CWC22

2

1

High-throughput

0.611

High

892772

H3
Histone H3

2

6

High-throughput

0.601

High

797313

SP381
Pre-mRNA-splicing factor SPP381

2

0

High-throughput

0.595

High

892801

RUXE
Small nuclear ribonucleoprotein E

2

2

High-throughput

0.588

High

892779

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

1

Small-scale

0.586

High

743532

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.586

High

628214

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

3

6

Small-scale

0.586

High

780836

MUD2
Splicing factor MUD2

2

0

Small-scale

0.570

High

594459

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

545508

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.536

High

722086

XPO1
Exportin-1

1

9

High-throughput

0.536

High

818019

LSM4
LSM complex subunit LSM4

1

3

High-throughput

0.536

High

892790

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

678703

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.508

High

656538

KC11
Casein kinase I homolog 1

1

14

High-throughput

0.501

High

865499

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

11

High-throughput

0.501

High

892765

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

Small-scale

0.481

High

892777

RPM2
Ribonuclease P protein component, mitochondrial

1

0

Small-scale

0.480

High

435222

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

442010

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

625030

PRP6
Pre-mRNA-splicing factor 6

1

10

High-throughput

0.479

High

625108

PRP9
Pre-mRNA-splicing factor PRP9

1

2

High-throughput

0.479

High

679858

CDC48
Cell division control protein 48

1

8

Small-scale

0.479

High

707606

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

751758

PRP8
Pre-mRNA-splicing factor 8

1

2

High-throughput

0.479

High

757505

NCBP1
Nuclear cap-binding protein complex subunit 1

1

5

High-throughput

0.479

High

780194

SN114
Pre-mRNA-splicing factor SNU114

1

9

High-throughput

0.479

High

796449

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.479

High

802273

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

829944

PRP17
Pre-mRNA-processing factor 17

1

14

High-throughput

0.479

High

847807

SMD3
Small nuclear ribonucleoprotein Sm D3

1

7

High-throughput

0.479

High

886343

PRP31
Pre-mRNA-processing factor 31

1

5

High-throughput

0.479

High

892775

SMD1
Small nuclear ribonucleoprotein Sm D1

1

2

High-throughput

0.479

High

892780

CWC21
Pre-mRNA-splicing factor CWC21

1

1

High-throughput

0.479

High

892784

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

892785

SYF1
Pre-mRNA-splicing factor SYF1

1

9

High-throughput

0.479

High

892789

SMD2
Small nuclear ribonucleoprotein Sm D2

1

2

High-throughput

0.479

High

892798

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

892799

BBP
Branchpoint-bridging protein

1

4

High-throughput

0.479

High

892802

PRP46
Pre-mRNA-splicing factor PRP46

1

15

High-throughput

0.479

High

892803

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

2

Small-scale

0.479

High

892778

SLU7
Pre-mRNA-splicing factor SLU7

1

0

Small-scale

0.460

High

638069

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

672061

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

702261

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

781571

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

797677

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

892766

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

892769

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.458

High

892783

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

892787

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.458

High

892788

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

892764

ATG1
Serine/threonine-protein kinase ATG1

1

18

High-throughput

0.457

High

393017

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

524512

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

527134

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

741946

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

742895

HSP79
Heat shock protein homolog SSE2

1

15

High-throughput

0.445

High

819227

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

892771

LSM3
LSM complex subunit LSM3

1

9

High-throughput

0.445

High

149857

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

410228

RL25
Large ribosomal subunit protein uL23

1

6

High-throughput

0.437

High

433736

RL26A
Large ribosomal subunit protein uL24A

1

5

High-throughput

0.437

High

436057

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

455156

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

503138

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504310

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

512539

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

514725

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

689553

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

747469

RSSA1
Small ribosomal subunit protein uS2A

1

7

High-throughput

0.437

High

778428

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

779556

LHS1
Heat shock protein 70 homolog LHS1

1

11

High-throughput

0.437

High

810850

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

892774

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

892794

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

752490

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

816298

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.407

High

863645

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

797760

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

812473

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

874417

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

892782

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025