HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: UBL1 (P35127)
Ubiquitin carboxyl-terminal hydrolase YUH1 (UCH) (EC 3.4.19.12) (Ubiquitin thioesterase)
Gene: YUH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.80	0.781

Property	Details
Experiments	10413498, 10512618, 19520148, 38803224
Identification Methods	x-ray crystallography, pull down
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 236
+	Mm
		477056 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UCHL5_MOUSE (1-234): 7.68e-100: 295: 21.61
+	Mm
		477030 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UCHL3_MOUSE (4-232): 7.53e-78: 235: 30.13
+	Mm
		476730 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UCHL4_MOUSE (4-232): 1.57e-74: 227: 28.93
+	Mm
		477047 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		UCHL1_MOUSE (10-233): 1.5e-67: 209: 25.43
+	Rn
		962731 UBC_RAT (1-333): 8.71e-131: 395: 93.99		UCHL1_RAT (10-233): 1.5e-67: 209: 25.43
+	Hs
		474910 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71
+	Hs
		548107 Q5U5U6_HUMAN (77-304): 5.9e-91: 274: 96.05		UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71
+	Hs
		456474 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57
+	Hs
		476639 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		UCHL5_HUMAN (1-234): 2.78e-99: 293: 21.61
+	Hs
		476130 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		BAP1_HUMAN (5-234): 1.09e-77: 249: 18.37
+	Hs
		475307 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71
+	Hs
		398154 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		UCHL5_HUMAN (1-234): 2.78e-99: 293: 21.61
+	Hs
		456475 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57
+	Sc
		408320 RS31_YEAST (305-380): 1.88e-41: 144: 100.00		UBL1_YEAST (1-236): 7.21e-81: 243: 100.00
+	Sc
		477613 RL40A_YEAST (305-380): 1.92e-41: 143: 100.00		UBL1_YEAST (1-236): 7.21e-81: 243: 100.00
+	Hs
		924096 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		BAP1_HUMAN (5-234): 1.09e-77: 249: 18.37
+	Hs
		456536 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57