HitPredict

Interactor 1: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Interactor 2: SERPH (P50454)
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
Gene: SERPINH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Serpin~fn3
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2347 Hs			1 418
+	Rn
		431479 INSR_RAT (1424-2308): 1.9e-165: 551: 23.29		SPA3K_RAT (5-409): 3.05e-165: 472: 23.97
+	Hs
		439683 INSR_HUMAN (1424-2308): 8.35e-168: 557: 23.23		SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00
+	Hs
		465461 IGF1R_HUMAN (1442-2307): 3.32e-163: 544: 22.98		SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00
+	Hs
		720162 UFO_HUMAN (1633-2297): 3.66e-130: 435: 25.83		SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00
+	Hs
		895677 ALK_HUMAN (1858-2311): 4.33e-84: 309: 38.96		SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00
+	Hs
		650090 FGFR3_HUMAN (1886-2215): 4.24e-59: 222: 38.73		SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00