HitPredict

Interactor 1: SERPH (P50454)
Serpin H1 (47 kDa heat shock protein) (Arsenic-transactivated protein 3) (AsTP3) (Cell proliferation-inducing gene 14 protein) (Collagen-binding protein) (Colligin) (Rheumatoid arthritis-related antigen RA-A47)
Gene: SERPINH1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 1620
+	Rn
		431479 SPA3K_RAT (5-409): 3.05e-165: 472: 23.97		INSR_RAT (973-1484): 1.46e-112: 392: 32.38
+	Hs
		477217 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		650090 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		439683 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465461 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		411591 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		411467 SPB6_HUMAN (43-409): 3.2e-151: 435: 29.52		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		895565 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541397 SERPH_HUMAN (1-418): 2.86e-152: 439: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07