HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 670
+	Hs
		872797 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DDX18_HUMAN (1-670): 4.04e-173: 511: 100.00
+	Ce
		145021 SSP1B_CAEEL (91-208): 5.62e-18: 83.7: 32.80		Q9N478_CAEEL (103-621): 2.61e-168: 500: 36.21
+	Hs
		1024206 TFAM_HUMAN (95-186): 2.96e-09: 57.1: 17.39		DDX18_HUMAN (1-670): 4.04e-173: 511: 100.00
+	Hs
		1065340 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		DDX17_HUMAN (99-603): 6.39e-133: 409: 24.75
+	Hs
		608560 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		DDX5_HUMAN (71-600): 1.1e-131: 403: 22.47
+	Hs
		872600 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DDX17_HUMAN (99-603): 6.39e-133: 409: 24.75
+	Hs
		608494 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DDX5_HUMAN (71-600): 1.1e-131: 403: 22.47
+	Hs
		141367 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DDX3X_HUMAN (17-564): 1.33e-129: 399: 22.59
+	Hs
		1369354 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		DDX17_HUMAN (99-603): 6.39e-133: 409: 24.75
+	Hs
		608708 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		DDX5_HUMAN (71-600): 1.1e-131: 403: 22.47
+	Hs
		141627 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		DDX3X_HUMAN (17-564): 1.33e-129: 399: 22.59
+	Hs
		872629 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		DDX27_HUMAN (121-573): 5.83e-56: 205: 34.75