HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 116
+	Hs
		48200 ESYT2_HUMAN (1-921): 0: 839: 100.00		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Hs
		48367 ESYT2_HUMAN (1-921): 0: 839: 100.00		VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03
+	Hs
		261693 SYT2_HUMAN (309-496): 7.51e-25: 110: 16.89		VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58
+	Hs
		263340 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Hs
		1079418 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03
+	Hs
		1079342 SYT6_HUMAN (376-618): 3.03e-19: 94.1: 21.81		VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03
+	Hs
		599560 SYT1_HUMAN (787-910): 3.15e-13: 74.7: 35.20		VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19
+	Rn
		600318 SYT1_RAT (787-910): 2.89e-13: 74.7: 35.20		VAMP2_RAT (2-75): 2.33e-25: 93.8: 39.19
+	Hs
		263404 PCLO_HUMAN (363-500): 2.77e-12: 73.3: 21.80		SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65
+	Mm
		802312 SYT2_MOUSE (315-513): 8.25e-10: 64.1: 18.22		VAMP2_MOUSE (2-75): 2.33e-25: 93.8: 39.19