HitPredict

Interactor 1: HMAL2 (P0CY09)
Silenced mating-type protein ALPHA2 (MATalpha2 protein) (Alpha-2 repressor)
Gene: HMLALPHA2

Interactor 2: MCM1 (P11746)
Pheromone receptor transcription factor (GRM/PRTF protein)
Gene: MCM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	7739902, 9490409, 8628280
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Homeodomain~SRF-TF
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 210 Sc			1 286
+	Sc
		483012 MTAL2_YEAST (1-210): 1.7e-141: 394: 100.00		MCM1_YEAST (1-286): 4.48e-47: 160: 100.00