HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 247
+	Hs
		48340 ESYT2_HUMAN (1-921): 0: 839: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		48275 ESYT2_HUMAN (1-921): 0: 839: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		982628 RIMS2_HUMAN (546-911): 6.39e-32: 137: 15.17		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		909970 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905058 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982437 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683675 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927470 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		927594 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		926842 Q8C8C0_MOUSE (802-912): 9.07e-13: 74.1: 22.32		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59