HitPredict

Interactor 1: TPC2B (P0DI82)
Trafficking protein particle complex subunit 2B (MBP-1-interacting protein 2A) (MIP-2A)
Gene: TRAPPC2B

Interactor 2: TPC10 (P48553)
Trafficking protein particle complex subunit 10 (Epilepsy holoprosencephaly candidate 1 protein) (EHOC-1) (Protein GT334) (Trafficking protein particle complex subunit TMEM1) (Transport protein particle subunit TMEM1) (TRAPP subunit TMEM1)
Gene: TRAPPC10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	28514442, 33961781, 35271311, 21525244
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006901 - vesicle coating GO:0030008 - TRAPP complex GO:0099022 - vesicle tethering and 1 others more... GO:1990071 - TRAPPII protein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1259
+	Hs
		483236 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		TPC10_HUMAN (1-1259): 0: 1894: 100.00
+	Hs
		819737 TPC2L_HUMAN (4-133): 2.81e-41: 135: 20.42		TPC10_HUMAN (1-1259): 0: 1894: 100.00
+	Dm
		1365344 TPPC2_DROME (3-140): 6.6e-59: 180: 57.97		TPC10_DROME (15-1248): 0: 1439: 28.98
+	Dm
		53203 A1Z8I0_DROME (4-133): 2.61e-42: 138: 25.71		TPC10_DROME (15-1248): 0: 1439: 28.98
+	Sc
		748771 TRS20_YEAST (6-138): 6.12e-48: 154: 33.53		TR130_YEAST (21-514): 2.29e-135: 443: 18.11