HitPredict

Interactor 1: TPC2B (P0DI82)
Trafficking protein particle complex subunit 2B (MBP-1-interacting protein 2A) (MIP-2A)
Gene: TRAPPC2B

Interactor 2: TPC11 (Q7Z392)
Trafficking protein particle complex subunit 11
Gene: TRAPPC11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	35271311, 21525244, 28514442, 33961781
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Foie-gras_1~Sedlin_N
Common GO terms	GO:0005737 - cytoplasm GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030008 - TRAPP complex GO:0048208 - COPII vesicle coating GO:0099022 - vesicle tethering and 1 others more... GO:1990072 - TRAPPIII protein complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1133
+	Hs
		483249 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		TPC11_HUMAN (1-1133): 0: 1735: 100.00
+	Hs
		1188134 TPC2L_HUMAN (4-133): 2.81e-41: 135: 20.42		TPC11_HUMAN (1-1133): 0: 1735: 100.00
+	Dm
		1215318 TPPC2_DROME (3-140): 6.6e-59: 180: 57.97		Q8IRE3_DROME (963-1120): 8.11e-12: 72.2: 26.47
+	Dm
		53201 A1Z8I0_DROME (4-133): 2.61e-42: 138: 25.71		Q8IRE3_DROME (963-1120): 8.11e-12: 72.2: 26.47