HitPredict

Interactor 1: CALM2 (P0DP24)
Calmodulin-2
Gene: CALM2

Interactor 2: PP2BC (P48454)
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)
Gene: PPP3CC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~Metallophos
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 149 Hs			1 512
+	Hs
		484083 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BC_HUMAN (1-512): 0: 844: 100.00
+	Hs
		483921 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BA_HUMAN (6-512): 0: 826: 80.59
+	Hs
		483996 CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BA_HUMAN (6-512): 0: 826: 80.59
+	Hs
		484113 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BA_HUMAN (6-512): 0: 826: 80.59
+	Hs
		483899 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BB_HUMAN (12-504): 0: 793: 82.66
+	Hs
		483972 CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BB_HUMAN (12-504): 0: 793: 82.66
+	Hs
		484057 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		PP2BB_HUMAN (12-504): 0: 793: 82.66
+	Dm
		906741 CALM_DROME (1-149): 5.63e-56: 173: 97.99		PP2B3_DROME (4-489): 0: 745: 75.00
+	Dm
		819188 CALL_DROME (3-149): 9.23e-57: 175: 66.67		PP2B1_DROME (7-481): 0: 721: 70.67
+	Dd
		361258 CALM_DICDI (47-148): 1.56e-09: 54.8: 30.10		PP2BA_DICDI (5-495): 0: 665: 53.71
+	Sc
		420231 CALM_YEAST (1-75): 2.74e-14: 67.4: 40.79		PP2B1_YEAST (8-487): 0: 630: 50.10
+	Sc
		420209 CALM_YEAST (1-75): 2.74e-14: 67.4: 40.79		PP2B2_YEAST (8-487): 0: 627: 48.70
+	Hs
		648468 CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56		PP1G_HUMAN (33-347): 7.16e-171: 486: 35.60
+	Zm
		11196 A0A1D6FBD8_MAIZE (11-112): 1.34e-09: 54.3: 32.04		B4FJL0_MAIZE (67-325): 1.6e-74: 240: 42.47
+	Pf
		907226 CALM_PLAF7 (1-149): 6.39e-55: 171: 89.26		Q8IAM8_PLAF7 (386-478): 2.03e-10: 65.4: 29.03