HitPredict

Interactor 1: ZTRF1 (P0DTL6)
Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1)
Gene: ZFTRAF1

Interactor 2: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 404 Hs			1 200
+	Dm
		854594 CYHR1_DROME (100-404): 1.51e-158: 454: 52.73		UBCD4_DROME (1-199): 3.1e-73: 221: 68.34
+	Hs
		896333 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00
+	Dm
		639400 SINAL_DROME (53-249): 7.44e-53: 181: 23.53		UBCD1_DROME (4-154): 2.12e-74: 222: 41.72
+	Dm
		854588 SINAL_DROME (53-249): 7.44e-53: 181: 23.53		UBCD4_DROME (1-199): 3.1e-73: 221: 68.34
+	Hs
		1216737 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72
+	Hs
		849364 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Dm
		854568 SINAL_DROME (53-249): 7.44e-53: 181: 23.53		UBCD2_DROME (3-153): 4.47e-68: 209: 41.72
+	Hs
		919778 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06
+	Hs
		895842 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74
+	Hs
		199099 SIAH2_HUMAN (98-249): 5.46e-44: 157: 25.64		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Dm
		598811 SINA_DROME (95-249): 9.91e-45: 159: 25.79		UBCD1_DROME (4-154): 2.12e-74: 222: 41.72
+	Dm
		598818 SINA_DROME (95-249): 9.91e-45: 159: 25.79		UBCD4_DROME (1-199): 3.1e-73: 221: 68.34
+	Hs
		1216686 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2E2_HUMAN (3-153): 3.57e-68: 208: 40.40
+	Hs
		1216680 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UB2E3_HUMAN (3-153): 8.99e-68: 207: 40.40
+	Hs
		72145 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		B3KSH4_HUMAN (104-200): 1.63e-61: 187: 100.00
+	Dm
		715099 SINAL_DROME (53-249): 7.44e-53: 181: 23.53		UBE2N_DROME (43-153): 2.22e-34: 120: 53.15
+	Dm
		1250208 SINAL_DROME (53-249): 7.44e-53: 181: 23.53		Q9VJS5_DROME (43-146): 7.55e-34: 119: 56.73
+	Hs
		896488 SIAH1_HUMAN (60-249): 5.09e-48: 166: 24.74		UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97
+	Dm
		598812 SINA_DROME (95-249): 9.91e-45: 159: 25.79		UBE2N_DROME (43-153): 2.22e-34: 120: 53.15
+	Dm
		598879 SINA_DROME (95-249): 9.91e-45: 159: 25.79		Q9VJS5_DROME (43-146): 7.55e-34: 119: 56.73