Interactor 1: GLI3 (P10071)
Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)]
Gene: GLI3

Interactor 2: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16371461
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005929 - cilium
GO:0016607 - nuclear speck
GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1580
Hs

1 337
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024