HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: NEDD8 (Q15843)
Ubiquitin-like protein NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 81
+	Hs
		172117 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00
+	Hs
		485044 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14
+	Hs
		650687 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		RS27A_HUMAN (1-77): 6.68e-37: 122: 57.14
+	Hs
		650688 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		RL40_HUMAN (1-76): 3.81e-33: 112: 57.90
+	Hs
		909588 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00
+	Hs
		650778 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00
+	Hs
		1154913 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00
+	Hs
		1120168 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00
+	Hs
		1154902 DAZP1_HUMAN (3-87): 1.54e-15: 79.4: 31.77		NEDD8_HUMAN (1-81): 2.08e-30: 103: 100.00