HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 334
+	Hs
		172163 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		909644 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		650886 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370324 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1120265 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370283 DAZP1_HUMAN (3-87): 1.54e-15: 79.4: 31.77		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1102046 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370347 RBM4_HUMAN (104-187): 6.5e-11: 65.2: 22.35		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		187868 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		EIF3H_HUMAN (52-320): 2.18e-66: 214: 18.57
+	Hs
		131302 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48