HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36950384
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 2581
+	Hs
		909706 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		650970 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		1120349 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		172085 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		485097 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		172107 HNRDL_HUMAN (2-282): 5.24e-72: 232: 33.56		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		909549 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		650722 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		485148 ROA1_HUMAN (1-372): 6.83e-64: 210: 100.00		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		909575 ROA3_HUMAN (7-202): 1.05e-56: 191: 85.71		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		650760 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1088528 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1132925 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1088334 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1088320 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1120155 HNRPD_HUMAN (2-99): 4.16e-18: 86.4: 24.00		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1101959 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		903385 RA1L2_HUMAN (1-302): 4.02e-61: 201: 83.44		SMCA4_HUMAN (69-1478): 0: 816: 23.14
+	Hs
		650650 ROA2_HUMAN (1-320): 2.13e-56: 189: 58.44		SMCA4_HUMAN (69-1478): 0: 816: 23.14
+	Hs
		1101977 PABP4_HUMAN (102-193): 4.58e-15: 78.7: 15.05		CHD9_HUMAN (2104-2481): 3.9e-107: 387: 29.62