HitPredict

Interactor 1: IF4A (P10081)
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
Gene: TIF1

Interactor 2: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33326013, 37845327
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006413 - translational initiation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 395 Sc			1 352
+	Sc
		485661 IF4A_YEAST (1-395): 9.95e-152: 435: 100.00		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		415898 DED1_YEAST (3-395): 1.27e-125: 376: 30.19		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		624024 DBP2_YEAST (1-392): 1.76e-131: 390: 31.42		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Sc
		415895 DED1_YEAST (3-395): 1.27e-125: 376: 30.19		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Sc
		633232 DHH1_YEAST (24-390): 2.1e-96: 298: 43.48		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		628064 DHH1_YEAST (24-390): 2.1e-96: 298: 43.48		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00