Protein: KPCT
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)

Gene: KPCT, PRKCQ
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q04759

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001772 - immunological synapse
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

981046

KPCT
Protein kinase C theta type

4

17

Small-scale

0.888

High

158451

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

4

20

Small-scale

0.881

High

167526

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

4

20

Small-scale

0.873

High

981061

DEFI6
Differentially expressed in FDCP 6 homolog

3

14

High-throughput

0.861

High

563591

ZNF24
Zinc finger protein 24

2

4

High-throughput

0.811

High

981048

KPCD
Protein kinase C delta type

2

18

High-throughput

0.811

High

412141

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.803

High

146966

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.770

High

411685

LCK
Tyrosine-protein kinase Lck

2

20

Small-scale

0.767

High

201310

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

9

Small-scale

0.754

High

981057

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

20

Small-scale

0.734

High

610363

CBL
E3 ubiquitin-protein ligase CBL

1

7

Small-scale

0.724

High

646820

1433T
14-3-3 protein theta

1

20

Small-scale

0.724

High

681799

AKT1
RAC-alpha serine/threonine-protein kinase

1

17

Small-scale

0.724

High

981060

CAR11
Caspase recruitment domain-containing protein 11

5

12

Small-scale

0.711

High

590168

CCNA2
Cyclin-A2

1

3

High-throughput

0.691

High

981047

KPCZ
Protein kinase C zeta type

1

17

Small-scale

0.683

High

981049

BTK
Tyrosine-protein kinase BTK

1

20

Small-scale

0.665

High

981056

GRP3
Ras guanyl-releasing protein 3

1

8

Small-scale

0.647

High

182138

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

19

Small-scale

0.618

High

431762

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

438094

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

548689

VAV
Proto-oncogene vav

1

11

Small-scale

0.618

High

647878

MARK3
MAP/microtubule affinity-regulating kinase 3

1

10

Small-scale

0.618

High

783987

KPCI
Protein kinase C iota type

1

18

Small-scale

0.618

High

895051

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.618

High

904468

1433G
14-3-3 protein gamma

1

20

Small-scale

0.618

High

981051

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

7

High-throughput

0.618

High

981062

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

981066

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.618

High

330245

BCL10
B-cell lymphoma/leukemia 10

2

4

Small-scale

0.601

High

280384

GLRX3
Glutaredoxin-3

1

6

Small-scale

0.586

High

981050

LCP2
Lymphocyte cytosolic protein 2

1

1

Small-scale

0.575

High

981059

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

1

Small-scale

0.561

High

981055

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

961062

HSF1
Heat shock factor protein 1

1

0

Small-scale

0.537

High

535725

LYAM1
L-selectin

1

3

Small-scale

0.527

High

981065

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

9

Small-scale

0.515

High

981063

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.513

High

981054

HABP4
Intracellular hyaluronan-binding protein 4

1

6

Small-scale

0.501

High

167753

FYB1
FYN-binding protein 1

1

2

Small-scale

0.479

High

527413

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

608270

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

5

Small-scale

0.479

High

823917

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.479

High

968771

MEF2A
Myocyte-specific enhancer factor 2A

1

1

Small-scale

0.479

High

981052

CUL3
Cullin-3

1

4

High-throughput

0.479

High

981058

AKAP1
A-kinase anchor protein 1, mitochondrial

1

4

High-throughput

0.479

High

981067

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

981068

NEMO
NF-kappa-B essential modulator

1

16

Small-scale

0.479

High

568203

TAL1
T-cell acute lymphocytic leukemia protein 1

1

2

Small-scale

0.439

High

568090

JUND
Transcription factor JunD

1

3

Small-scale

0.437

High

720281

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

981064

MTCH1
Mitochondrial carrier homolog 1

1

15

High-throughput

0.437

High

499353

CD28
T-cell-specific surface glycoprotein CD28

1

0

Small-scale

0.426

High

981053

CRY1
Cryptochrome-1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024