HitPredict

Interactor 1: IF4A (P10081)
ATP-dependent RNA helicase eIF4A (EC 3.6.4.13) (Eukaryotic initiation factor 4A) (eIF-4A) (Stimulator factor I 37 kDa component) (Translation initiation factor 1/2) (p37)
Gene: TIF1

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	15590687, 23403034
Identification Methods	affinity chromatography technology, protein complementation assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 395 Sc			1 101
+	Hs
		892765 IF4A1_HUMAN (9-394): 1.03e-170: 484: 66.24		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		1140379 Q6P3V8_RAT (9-394): 1.03e-170: 484: 66.24		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		902582 IF4A2_HUMAN (8-394): 2.32e-170: 483: 65.04		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		902699 DDX17_HUMAN (1-395): 1.81e-132: 398: 31.85		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		1140372 Q6AYI1_RAT (1-394): 4.09e-133: 396: 31.27		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		571381 DDX5_HUMAN (1-394): 2.34e-132: 394: 31.27		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		133955 DDX3X_HUMAN (3-393): 2.68e-129: 388: 29.95		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		89015 D4ADE8_RAT (3-393): 2.33e-128: 385: 29.95		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96