HitPredict

Interactor 1: RAP2A (P10114)
Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30)
Gene: RAP2A

Interactor 2: RASF5 (Q8WWW0)
Ras association domain-containing protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL)
Gene: RASSF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.80	0.608

Property	Details
Experiments	11857081
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, RA~Ras
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 418
+	Hs
		897989 RAP2B_HUMAN (1-182): 2.01e-82: 243: 91.21		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		919655 RAP1A_HUMAN (1-182): 1.35e-81: 241: 61.75		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Mm
		1125491 RAP1B_MOUSE (1-182): 4.24e-79: 234: 60.66		RASF5_MOUSE (3-418): 0: 574: 85.10
+	Hs
		897926 RAP1B_HUMAN (1-182): 4.24e-79: 234: 60.66		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Mm
		1125490 RASH_MOUSE (1-180): 3.16e-48: 156: 46.49		RASF5_MOUSE (3-418): 0: 574: 85.10
+	Hs
		349532 RASH_HUMAN (1-180): 3.16e-48: 156: 46.49		RASF5_HUMAN (1-418): 0: 574: 100.00
+	Hs
		349676 RASH_HUMAN (1-180): 3.16e-48: 156: 46.49		RASF1_HUMAN (87-410): 5.15e-145: 418: 45.10
+	Hs
		349196 RASH_HUMAN (1-180): 3.16e-48: 156: 46.49		RASF2_HUMAN (223-418): 2.59e-56: 190: 26.96