Interactor 1: GRAB (P10144)
Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Gene: GZMB

Interactor 2: BID (P55957)
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
Gene: BID

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 17283187, 15569669, 17179148, 10805722, 16415351, 12808108, 11696597, 15014070, 19103589
Identification Methods enzymatic study, protease assay
Interaction Type direct interaction, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0016020 - membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 247
Hs

1 195
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024