HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: ABL2 (P42684)
Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson tyrosine-protein kinase 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)
Gene: ABL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1182
+	Hs
		337320 ANDR_HUMAN (1-920): 0: 966: 100.00		ABL1_HUMAN (58-1182): 0: 784: 51.21
+	Hs
		433225 ANDR_HUMAN (1-920): 0: 966: 100.00		YES_HUMAN (21-556): 0: 551: 38.14
+	Hs
		487088 ANDR_HUMAN (1-920): 0: 966: 100.00		SRC_HUMAN (24-556): 0: 549: 38.12
+	Hs
		487364 ANDR_HUMAN (1-920): 0: 966: 100.00		BTK_HUMAN (61-547): 1.36e-178: 541: 37.30
+	Hs
		442764 ANDR_HUMAN (1-920): 0: 966: 100.00		HCK_HUMAN (36-554): 5.53e-177: 532: 36.96
+	Hs
		454790 ANDR_HUMAN (1-920): 0: 966: 100.00		FGR_HUMAN (32-556): 2.64e-175: 528: 38.32
+	Hs
		411564 ANDR_HUMAN (1-920): 0: 966: 100.00		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		433537 ANDR_HUMAN (1-920): 0: 966: 100.00		LYN_HUMAN (57-554): 3.14e-168: 509: 36.58
+	Hs
		487245 ANDR_HUMAN (1-920): 0: 966: 100.00		BLK_HUMAN (52-554): 2.43e-163: 496: 38.52
+	Hs
		368834 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		YES_HUMAN (21-556): 0: 551: 38.14
+	Hs
		368894 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SRC_HUMAN (24-556): 0: 549: 38.12
+	Mm
		403414 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		SRC_MOUSE (24-556): 0: 551: 38.01
+	Rn
		411266 ESR1_RAT (378-904): 2.19e-130: 406: 20.94		SRC_RAT (24-556): 0: 547: 37.94
+	Hs
		377057 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SRC_HUMAN (24-556): 0: 549: 38.12
+	Hs
		377007 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		FYN_HUMAN (42-556): 0: 547: 38.91
+	Hs
		522762 RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84		SRC_HUMAN (24-556): 0: 549: 38.12
+	Hs
		433435 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		YES_HUMAN (21-556): 0: 551: 38.14
+	Hs
		523091 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		SRC_HUMAN (24-556): 0: 549: 38.12
+	Hs
		377006 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		LCK_HUMAN (56-554): 7.83e-175: 526: 38.87
+	Hs
		414427 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		SRC_HUMAN (24-556): 0: 549: 38.12