Protein: PARP1
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (msPARP) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (Poly [ADP-ribose] polymerase 1, 24-kDa form)]

Gene: PARP1
Organism: Mus musculus
Interactions: 18
UniProt ID: P11103

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000723 - telomere maintenance
GO:0000785 - chromatin
GO:0003684 - damaged DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

536212

PO5F1
POU domain, class 5, transcription factor 1

1

6

High-throughput

0.500

High

536216

HDAC2
Histone deacetylase 2

1

14

Small-scale

0.500

High

536220

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.500

High

536226

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

6

Small-scale

0.500

High

536213

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

1

Small-scale

0.479

High

536221

OTUD5
OTU domain-containing protein 5

1

7

Small-scale

0.479

High

536222

E2F1
Transcription factor E2F1

1

5

Small-scale

0.479

High

536224

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

5

Small-scale

0.479

High

536225

HDAC9
Histone deacetylase 9

1

5

Small-scale

0.479

High

536214

TRAF1
TNF receptor-associated factor 1

1

2

High-throughput

0.457

High

536228

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

3

High-throughput

0.457

High

148269

CLOCK
Circadian locomoter output cycles protein kaput

1

7

Small-scale

0.445

High

536215

HMGA2
High mobility group protein HMGI-C

1

4

High-throughput

0.445

High

536217

TBX5
T-box transcription factor TBX5

1

2

Small-scale

0.445

High

536218

CASP3
Caspase-3

1

9

Small-scale

0.445

High

536219

CASP7
Caspase-7

1

9

Small-scale

0.445

High

536223

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

4

High-throughput

0.445

High

536227

AIRE
Autoimmune regulator

1

20

Small-scale

0.445

High


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Last updated: 11Aug2025