HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: FOXG1 (P55316)
Forkhead box protein G1 (Brain factor 1) (BF-1) (BF1) (Brain factor 2) (BF-2) (BF2) (hBF-2) (Forkhead box protein G1A) (Forkhead box protein G1B) (Forkhead box protein G1C) (Forkhead-related protein FKHL1) (HFK1) (Forkhead-related protein FKHL2) (HFK2) (Forkhead-related protein FKHL3) (HFK3)
Gene: FOXG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	17482455
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 489
+	Hs
		487575 ANDR_HUMAN (1-920): 0: 966: 100.00		FOXP4_HUMAN (55-340): 6.09e-54: 194: 27.59
+	Hs
		487378 ANDR_HUMAN (1-920): 0: 966: 100.00		FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90
+	Hs
		487336 ANDR_HUMAN (1-920): 0: 966: 100.00		FOXK1_HUMAN (71-309): 9.43e-50: 183: 31.15
+	Hs
		206792 ANDR_HUMAN (1-920): 0: 966: 100.00		FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70
+	Hs
		487270 ANDR_HUMAN (1-920): 0: 966: 100.00		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84
+	Hs
		369425 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		FOXK2_HUMAN (67-456): 6.09e-58: 204: 24.64
+	Hs
		369487 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90
+	Hs
		369403 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		FOXK1_HUMAN (71-309): 9.43e-50: 183: 31.15
+	Hs
		206786 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70
+	Hs
		369258 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84
+	Mm
		291643 ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30		FOXL2_MOUSE (134-324): 2.51e-47: 169: 37.70
+	Hs
		1217548 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		FOXP4_HUMAN (55-340): 6.09e-54: 194: 27.59
+	Hs
		952844 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		FOXK1_HUMAN (71-309): 9.43e-50: 183: 31.15
+	Hs
		377289 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		FOXL1_HUMAN (155-288): 2.31e-48: 171: 47.02
+	Hs
		206846 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		FOXO3_HUMAN (59-468): 1.2e-48: 179: 20.70
+	Mm
		139020 ESR2_MOUSE (421-913): 2.91e-119: 375: 22.63		FOXL2_MOUSE (134-324): 2.51e-47: 169: 37.70
+	Hs
		622804 COT2_HUMAN (492-900): 2.13e-109: 345: 19.07		FOXP4_HUMAN (55-340): 6.09e-54: 194: 27.59
+	Hs
		487956 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		FOXO1_HUMAN (60-474): 2.23e-51: 186: 22.90
+	Hs
		487931 RARA_HUMAN (460-902): 8.57e-110: 348: 19.87		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84
+	Hs
		622779 COT2_HUMAN (492-900): 2.13e-109: 345: 19.07		FOXA1_HUMAN (80-448): 8.86e-50: 178: 22.84