HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35785414
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 1368
+	Hs
		370690 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		1269910 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		782691 HNF4A_HUMAN (536-906): 1e-104: 335: 22.85		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Mm
		1142670 ERR2_MOUSE (467-904): 1.62e-109: 346: 23.64		MED23_MOUSE (1-1368): 0: 2083: 96.27